I'm new here, so HELLO ALL!

Anyone using Clamwin to scan d/l's?

Parameters should be...

however this results in Clam notice that it's unable to access the file. I'm reporting this here because these parms do work with other applications, but not eMule +. I wonder eMule + is launching Clam before the file is actually copied to the download dir?

I did have this problem before when putting %1 in quotes with another application, but removing the quotes worked. With eMule +, neither works.

Are your incoming and temp folders on the same HDD partition?

Yes, they are, but both directories have been changed from the default (which would've been on C:) to a different drive. Directory structure:

C:\apps\emule (program directory)
D:\downloads\emule (finished d/l's)
D:\downloads\emule\temp (temp files)

%1 is a parameter for a batch file and it is probably substituted with a file or directory name when you run it. eMule Plus can't do the same as it is not a batch file processor.
eMule Plus runs it like this (command line):
AVSoftwareName SpecifiedByUserParameters "FileNameToCheck"

So you need to find a way to use switches in another way, or you can create an additional batch file contained:
and configure eMule Plus to run that batch file (instead of A/V software) without any parameters (leave it empty).